Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq of dissected cardiac septa from a mouse developmental time course


ABSTRACT: For this project, we explored the genetic determinants of the heart development condition termed patent foramen ovale (PFO) using quantitative trait loci (QTL) mapping and genomics/transcriptomics analyses. Two mice strains were chosen that exhibit highly divergent phenotypes associated with PFO, 129T2/SvEms and QSi5. In this experiment, we performed bulk RNA sequencing (RNA-seq) on the dissected septa from the hearts of developing 129T2/SvEms or QSi5 mice at three developmental time points: E12.5, E14.5 and E16.5. Each sample contained a pool of RNA from 3 dissected septa.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Mus musculus

SUBMITTER: Ralph Patrick 

PROVIDER: E-MTAB-10929 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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