Unknown,Transcriptomics,Genomics,Proteomics

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3' RNAseq of EGFR mutant lung cancer cell line overexpressing BRAF V600E treated with inhibitors


ABSTRACT: In the human EGFR mutant adenocarcinoma cell line PC9 pBabe empty vector (EV) or BRAF V600E were overexpressed. RNA was extracted from EV, BRAF V600E overexpressing or osimertinib-resistant BRAF V600E expressing cells after 48h treatment with osimertinib, trametinib, a combination of both or vehicle controls. RNA was subjected to 3' UTR RNA sequencing.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Johannes Braegelmann 

PROVIDER: E-MTAB-11004 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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