Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina Genome Analyzer IIx
ORGANISM(S): Homo sapiens
SUBMITTER: Amit Dutt
PROVIDER: E-MTAB-11407 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Das Poulami P Bansal Akanksha A Rao Sudha Narayan SN Deodhar Kedar K Mahantshetty Umesh U Shrivastava Shyam K SK Sivaraman Karthikeyan K Mulherkar Rita R
PloS one 20161109 11
There are very few reports that describe the mutational landscape of cervical cancer, one of the leading cancers in Indian women. The aim of the present study was to investigate the somatic mutations that occur in cervical cancer. Whole exome sequencing of 10 treatment naïve tumour biopsies with matched blood samples, from a cohort of Indian patients with locally advanced disease, was performed. The data revealed missense mutations across 1282 genes, out of 1831 genes harbouring somatic mutation ...[more]