ChIP-seq in wild type and Bmi1 knockdown undifferentiated spermatogonia
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ABSTRACT: Mammalian spermatogenesis is regulated by epigenetic mechanisms that maintain cell type-specific transcriptional programs. The epigenetic regulator BMI1, a PRC1 member, is required for maintaining undifferentiated spermatogonia, but the underlying mechanisms remain unclear. To address this issue, here we performed chromatin immunoprecipitation followed by massive parallel sequencing (ChIP-seq).
INSTRUMENT(S): Illumina NovaSeq 6000
ORGANISM(S): Mus musculus
SUBMITTER:
PROVIDER: E-MTAB-11778 | biostudies-arrayexpress |
SECONDARY ACCESSION(S): ERP138398
REPOSITORIES: biostudies-arrayexpress
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