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Single cell RNA-sequencing of cells isolated from full-thickness surgically resected tissue from stricturing and non-stricturing segments of the ileum of Crohn's disease patients

ABSTRACT: Intestinal fibrosis and stricture formation is an aggressive complication of Crohn’s disease (CD) and there is a clear unmet need for new therapies based on a better understanding of disease mechanisms. Knowledge of fibroblast heterogeneity is important as disease-state specific cell types represent important therapeutic targets. A lack of validated cell markers currently hampers progress.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER: David Humphreys

PROVIDER: E-MTAB-11792 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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