DNA methylation and gene expression analyses in adipose tissue to identify new loci associated with T2D development in obesity
Ontology highlight
ABSTRACT: Our study seeked to identify changes in DNA methylation and gene expression that might underlie type 2 diabetes susceptibility. We investigated DNA methylation and gene expression in VAT biopsies from 19 women with obesity, without (n=9) or with T2D (n=10). We analyzed and compared the methylome and transcriptome of visceral adipose tissue biopsies of women with obesity, with and without type 2 diabetes. Differential methylation and expression where then paired to test for Pearson's correlation to measure their relationship.
ORGANISM(S): Homo sapiens
SUBMITTER: Francisco Barajas
PROVIDER: E-MTAB-11841 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
ACCESS DATA