Microarrays of human pDCs derived from Rheumatoid Arthritis (RA) patients in remission (responding to anti-TNF agents) versus pDCs from healthy donors

ABSTRACT: In Rheumatoid Arthritis, restoration of immune self-tolerance represents an unmet therapeutic need, since a significant proportion of RA patients show inadequate clinical response. Based on the previously described tolerogenic phenotype of pDCs in RA responding to anti-TNF agents, we aimed to explore the molecular mechanisms involved in the tolerogenic reprogramming of pDCs in RA.

ORGANISM(S): Homo sapiens

SUBMITTER: Panagiota Goutakoli 

PROVIDER: E-MTAB-11933 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress