Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: nicolas buchon
PROVIDER: E-MTAB-1200 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Buchon Nicolas N Broderick Nichole A NA Poidevin Mickael M Pradervand Sylvain S Lemaitre Bruno B
Cell host & microbe 20090201 2
Although Drosophila systemic immunity is extensively studied, little is known about the fly's intestine-specific responses to bacterial infection. Global gene expression analysis of Drosophila intestinal tissue to oral infection with the Gram-negative bacterium Erwinia carotovora revealed that immune responses in the gut are regulated by the Imd and JAK-STAT pathways, but not the Toll pathway. Ingestion of bacteria had a dramatic impact on the physiology of the gut that included modulation of st ...[more]