MicroRNA profiling of fetal lamb heart treated with coiled implantation in left atrium against untreated controls
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ABSTRACT: We created a fetal lamb model of hypoplastic left heart syndrome (HLHS), by implanting coils in the left atrium in mid-gestation. We performed bulk RNA sequencing of left ventricles (LV), right ventricles (RV), ascending aortae (AAo) and pulmonary arteries (PA). Single nucleus RNA sequencing was performed on LV free wall tissue (n = 4 coiled samples, n = 3 controls).
INSTRUMENT(S): Illumina HiSeq 2500
ORGANISM(S): Ovis aries
SUBMITTER:
PROVIDER: E-MTAB-12230 | biostudies-arrayexpress |
SECONDARY ACCESSION(S): ERP141366
REPOSITORIES: biostudies-arrayexpress
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