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RNA-seq of fetal lamb heart treated with coiled implantation in left atrium against untreated controls

ABSTRACT: We created a fetal lamb model of hypoplastic left heart syndrome (HLHS), by implanting coils in the left atrium in mid-gestation. We performed bulk RNA sequencing of left ventricles (LV), right ventricles (RV), ascending aortae (AAo) and pulmonary arteries (PA). Single nucleus RNA sequencing was performed on LV free wall tissue (n = 4 coiled samples, n = 3 controls).

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Ovis aries

SUBMITTER:

PROVIDER: E-MTAB-12327 | biostudies-arrayexpress |

SECONDARY ACCESSION(S): ERP142035

REPOSITORIES: biostudies-arrayexpress

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microRNA profiling of fetal lamb heart treated with coiled implantation in left atrium against untreated controls

Project description:We created a fetal lamb model of hypoplastic left heart syndrome (HLHS), by implanting coils in the left atrium in mid-gestation. We performed bulk RNA sequencing of left ventricles (LV), right ventricles (RV), ascending aortae (AAo) and pulmonary arteries (PA). Single nucleus RNA sequencing was performed on LV free wall tissue (n = 4 coiled samples, n = 3 controls).

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Mouse model of myocardial infarction

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