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2 Role of aldehyde dehydrogenase on the metabolic regulation in Clostridium ljungdahlii fermentation

ABSTRACT: Clostridium ljungdahlii can utilize CO as energy source during autotrophic growth. C. ljungdahlii grows sufficiently in CO and produces ethanol as the main product. In this study, C. ljungdahlii wild type and mutant were fermented on CO. C. ljungdahlii produced more ethanol than the ΔadhE1 mutant. The results showed that aldehyde dehydrogenase inactivation led to inefficient metabolism in C. ljungdahlii. Thus, comparative transcriptomes among cells grown on CO of WT and ΔadhE1 mutant were performed to investigate gene expression profiles based on three biological replicates.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Clostridium ljungdahlii

SUBMITTER: Liu Ziyong

PROVIDER: E-MTAB-13021 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Role of aldehyde dehydrogenase on the metabolic regulation in Clostridium ljungdahlii fermentation

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