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TraDIS-Xpress to determine E. coli response to Piperacillin and Tazobactam separately and in combination

ABSTRACT: Found how E. coli responds to the commonly prescribed antibiotic-inhibitor combination piperacillin and tazobactam, separately and in combination. TraDIS-Xpress was performed following the protocol outlined by Yasir et al 2020 Genome Research. The results suggest tazobactam triggers the activity of multidrug efflux systems that have been previously seen to confer clinical resistance to multiple classes of antibiotics.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Escherichia coli

SUBMITTER: emma holden

PROVIDER: E-MTAB-13226 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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