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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq of Arcobacter butzleri RM4018 wild-type and Abu0127 deletion mutant under microaerophilic and paraquat stress conditions

ABSTRACT: We performed transcriptome (RNA-seq) analyses for Arcobacter butzleri RM4018 wild-type (WT) and Abu0127 deletion mutant (ΔAbu0127::aphA-3) under oxidative stress and optimal microaerobic growth conditions. The expression of 290 genes was affected by oxidative stress in stressed wild-type cells (WTS) compared to non-stressed cells (WT). A comparison of genes expressed in the ΔAbu0127 and WT strains under optimal growth conditions revealed 779 differently expressed genes. Moreover, transcriptional changes and overall final protein levels correlated across multiple genes. The data were validated through RT-qPCR and phenotype experiments for selected processes.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Aliarcobacter butzleri

SUBMITTER: Mateusz Noszka

PROVIDER: E-MTAB-13649 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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