Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq of thyroid cancer cell line upon silencing of RAIN, a RUNX2 associated intergenic lncRNA, and RUNX2


ABSTRACT: The aim of this experiment was to identify the RUNX2- and RAIN-dependent transcriptional program in thyroid cancer. TPC1 and MDA-T41 cell line were infected with dCas9-KRAB and sgRNA targeting the gene of interest (RAIN or RUNX2 respectively) or a non-targeting (NT) sgRNA as control. RNA was collected 10 days after infection and changes in gene expression were evaluated by total RNA-seq.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER:  

PROVIDER: E-MTAB-13777 | biostudies-arrayexpress |

SECONDARY ACCESSION(S): E-MTAB-11049

REPOSITORIES: biostudies-arrayexpress

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