APMAT analysis reveals associations between antigen-TCR sequences and CD8 T cell phenotype in COVID-19 patients
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ABSTRACT: Here, we describe Antigen-TCR Pairing and Multiomic Analysis of T-cells (APMAT), which is an integrated experimental-computational framework designed for the high-throughput capture and analysis of antigen specific CD8 T cells, with paired antigen, TCR sequence, and transcriptome information from the same single cells, from many patient samples in parallel.
INSTRUMENT(S): 10X genomics Chromium X, Illumina NovaSeq 6000, BD FACSAriaII cell sorter
ORGANISM(S): Homo sapiens
SUBMITTER: Jingyi Xie
PROVIDER: E-MTAB-14002 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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