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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq of mouse brain tissue investigating the effect of absence of microglia in the developing brain

ABSTRACT: Microglia, brain-resident macrophages, have been proposed to play an active role in synaptic refinement and maturation, influencing plasticity and circuit-level connectivity. Using a genetically modified mouse which lacks microglia (Csf1r ∆FIRE/∆FIRE), we investigate the effect on gene expression of the presence or absence of microglia in the developing mouse brain.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Owen Dando

PROVIDER: E-MTAB-14156 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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