Unknown,Transcriptomics,Genomics,Proteomics

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CASPAR survival analysis

ABSTRACT: This set of profiles was utilized to construct, validate and evaluate a gene-expression based classifier of outcome of neuroblastoma patients

ORGANISM(S): Homo sapiens

SUBMITTER: Andre Oberthuer

PROVIDER: E-MTAB-16 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Subclassification and individual survival time prediction from gene expression data of neuroblastoma patients by using CASPAR.

Oberthuer André A Kaderali Lars L Kahlert Yvonne Y Hero Barbara B Westermann Frank F Berthold Frank F Brors Benedikt B Eils Roland R Fischer Matthias M

Clinical cancer research : an official journal of the American Association for Cancer Research 20081001 20

<h4>Purpose</h4>To predict individual survival times for neuroblastoma patients from gene expression data using the cancer survival prediction using automatic relevance determination (CASPAR) algorithm.<h4>Experimental design</h4>A first set of oligonucleotide microarray gene expression profiles comprising 256 neuroblastoma patients was generated. Then, CASPAR was combined with a leave-one-out cross-validation to predict individual times for both the whole cohort and subgroups of patients with u ...[more]

PMID: 18927300

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Dataset Information

CASPAR survival analysis

Publications

Subclassification and individual survival time prediction from gene expression data of neuroblastoma patients by using CASPAR.

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