Unknown,Transcriptomics,Genomics,Proteomics

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Aspergillus fumigatus Af293 response to lactic acid bacteria antifungal activity


ABSTRACT: The effect of cell free supernatant from the antifungal strain Lactobacillus plantarum 16 on the growth of Aspergillus fumigatus Af293 was assessed. Transcriptome analysis of the genome was performed after ten minutes exposure to antifungal supernatant in order to determine the molecular targets involved in inhibtion.

ORGANISM(S): Aspergillus fumigatus

SUBMITTER: Sarah Crowley 

PROVIDER: E-MTAB-1701 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Transcriptomic and morphological profiling of Aspergillus fumigatus Af293 in response to antifungal activity produced by Lactobacillus plantarum 16.

Crowley Sarah S   Mahony Jennifer J   Morrissey John P JP   van Sinderen Douwe D  

Microbiology (Reading, England) 20130722 Pt 10


The morphological effects of an antifungal activity produced by Lactobacillus plantarum 16, a malt-production steep water isolate, on two food-associated fungi were examined microscopically. Spore germination was completely inhibited in Aspergillus fumigatus and Rhizopus stolonifer upon treatment with concentrated cell-free supernatant (cCFS) of strain 16. Furthermore, addition of antifungal cCFS to germ tubes and hyphae halted further development compared to untreated controls. Transcriptome an  ...[more]

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