Protein profiling of human serum against a panel of allergens.
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Katinka Vigh-Conrad
PROVIDER: E-MTAB-177 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
A protein allergen microarray detects specific IgE to pollen surface, cytoplasmic, and commercial allergen extracts.
Vigh-Conrad Katinka A KA Conrad Donald F DF Preuss Daphne D
PloS one 20100416 4
<h4>Background</h4>Current diagnostics for allergies, such as skin prick and radioallergosorbent tests, do not allow for inexpensive, high-throughput screening of patients. Additionally, extracts used in these methods are made from washed pollen that lacks pollen surface materials that may contain allergens.<h4>Methodology/principal findings</h4>We sought to develop a high-throughput assay to rapidly measure allergen-specific IgE in sera and to explore the relative allergenicity of different pol ...[more]
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