Transcriptional profiling of ovarian cancer samples with different grades
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Luca Beltrame
PROVIDER: E-MTAB-1814 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Wiring miRNAs to pathways: a topological approach to integrate miRNA and mRNA expression profiles.
Calura Enrica E Martini Paolo P Sales Gabriele G Beltrame Luca L Chiorino Giovanna G D'Incalci Maurizio M Marchini Sergio S Romualdi Chiara C
Nucleic acids research 20140506 11
The production rate of gene expression data is nothing less than astounding. However, with the benefit of hindsight we can assert that, since we completely ignored the non-coding part of the transcriptome, we spent the last decade to study cell mechanisms having few data in our hands. In this scenario, microRNAs, which are key post-trascriptional regulators, deserve special attention. Given the state of knowledge about their biogenesis, mechanisms of action and the numerous experimentally valida ...[more]
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