Chip_CMS_treatment
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Elena Bouzinova
PROVIDER: E-MTAB-1857 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Molecular profiling of the lateral habenula in a rat model of depression.
Christensen Trine T Jensen Line L Bouzinova Elena V EV Wiborg Ove O
PloS one 20131205 12
<h4>Objective</h4>This study systematically investigated the effect of chronic mild stress and response to antidepressant treatment in the lateral habenula at the whole genome level.<h4>Methods</h4>Rat whole genome expression chips (Affymetrix) were used to detect gene expression regulations in the lateral habenula of rats subjected to chronic mild stress (mild stressors exchanged twice a day for 8 weeks). Some rats received antidepressant treatment during fifth to eights week of CMS. The latera ...[more]
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