Dataset Information
CEU_ARRAY60
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Stephen Stephen Montgomery
PROVIDER: E-MTAB-198 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.
PLoS genetics 20100401 4
The recent success of genome-wide association studies (GWAS) is now followed by the challenge to determine how the reported susceptibility variants mediate complex traits and diseases. Expression quantitative trait loci (eQTLs) have been implicated in disease associations through overlaps between eQTLs and GWAS signals. However, the abundance of eQTLs and the strong correlation structure (LD) in the genome make it likely that some of these overlaps are coincidental and not driven by the same fun ...[more]
