Transcription profiling by array Saccharomyces cerevisiae after GGTI-298 treatment.
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ABSTRACT: Global gene expression on yeast cells was determined after a drug induced inhibition of GGTase I by treating yeast cells with GGTI298 (Cabiochem). GGTI298 treated cells were grown for 2 generations to exponential phase in parallel with untreated cells. RNA was extracted, subsequently cDNAs were labelled and hybridized on UHN Y6.4k4 arrays. Replicates with dye-swap of the experiments were generated. Results enabled us to identify the genome-wide effects after drug-induced GGTase I inhibition
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Giampiero Porcu
PROVIDER: E-MTAB-217 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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