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Healthy Antrum miRnome

ABSTRACT: A small RNA library of stomach antrum tissue was sequenced using high-throughput SOLiD sequencing technology. The study aims to provide complementary information of the role of miRNAs in molecular regulation process in the healthy human stomach, in order to establish a reference for future comparisons of altered miRNA expression due to the gastric tract diseases.

INSTRUMENT(S): AB SOLiD System 3.0

ORGANISM(S): Homo sapiens

SUBMITTER: Andre Ribeiro dos Santos

PROVIDER: E-MTAB-2273 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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MiRNA expression profile for the human gastric antrum region using ultra-deep sequencing.

Moreira Fabiano Cordeiro FC Assumpção Monica M Hamoy Igor G IG Darnet Sylvain S Burbano Rommel R Khayat André A Gonçalves André Nicolau AN Alencar Dayse O DO Cruz Aline A Magalhães Leandro L Araújo Wilson W Silva Artur A Santos Sidney S Demachki Samia S Assumpção Paulo P Ribeiro-dos-Santos Andrea A

PloS one 20140319 3

<h4>Background</h4>MicroRNAs are small non-coding nucleotide sequences that regulate gene expression. These structures are fundamental to several biological processes, including cell proliferation, development, differentiation and apoptosis. Identifying the expression profile of microRNAs in healthy human gastric antrum mucosa may help elucidate the miRNA regulatory mechanisms of the human stomach.<h4>Methodology/principal findings</h4>A small RNA library of stomach antrum tissue was sequenced u ...[more]

PMID: 24647245

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