Ontology highlight
ABSTRACT:
INSTRUMENT(S): AB SOLiD 4 System
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: David Talavera
PROVIDER: E-MTAB-2567 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Kershaw Christopher J CJ Costello Joseph L JL Castelli Lydia M LM Talavera David D Rowe William W Sims Paul F G PF Ashe Mark P MP Hubbard Simon J SJ Pavitt Graham D GD Grant Chris M CM
PLoS genetics 20150108 1
The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Slf1p and Sro9p are atypical-La motif containing proteins which are members of a superfamily of RNA-binding proteins conserved in eukaryotes. RIP-Seq analysis of these two yeast proteins identified overlapping and distinct sets of mRNA targets, including highly translated mRNAs such as those encoding ribosomal proteins. In paralell, transcriptome analysis of slf1Δ and sro9Δ mutant strains ...[more]