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MicroRNA profiling in aortic stenosis

ABSTRACT: We compared 15 severely diseased aortic valve sample to 16 control aortic valve samples using microRNA microarrays (Affymetrix GeneChip miRNA 2.0). The diseased samples were taken from areas of severe disease of aortic valves removed at aortic valve replacement for severe aortic stenosis. Control samples were obtained from macroscopically normal post-mortem aortic valves. In addition, we compared areas of mild or moderate disease on valves from participants with severe aortic stenosis to the same participant's severely diseased sample in seven participants.

ORGANISM(S): Homo sapiens

SUBMITTER: Sean Coffey

PROVIDER: E-MTAB-2766 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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