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Unknown,Transcriptomics,Genomics,Proteomics

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HIGHLY EXPRESSED GENES IN RAPIDLY PROLIFERATING TUMOR CELLS AS NEW TARGETS FOR COLORECTAL CANCER TREATMENT

ABSTRACT: The clinical management of colorectal cancer patients has significantly improved due to the identification of new chemotherapeutic targets. Since rapid tumor proliferation is associated with poor patient prognosis, here we characterize the transcriptional signature of rapidly proliferating colorectal cancer cells in an attempt to identify novel candidate therapeutic targets. Therefore, the doubling time of 52 colorectal cancer cell lines was determined and genome-wide expression profiling of a subset of 31 of these cell lines was assessed by microarray analysis.

ORGANISM(S): Homo sapiens

SUBMITTER: Diego Arango

PROVIDER: E-MTAB-2971 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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