Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2000
ORGANISM(S): Mus musculus domesticus
SUBMITTER: Anna Lorenc
PROVIDER: E-MTAB-3304 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
The New England journal of medicine 20140830 11
<h4>Background</h4>We compared the angiotensin receptor-neprilysin inhibitor LCZ696 with enalapril in patients who had heart failure with a reduced ejection fraction. In previous studies, enalapril improved survival in such patients.<h4>Methods</h4>In this double-blind trial, we randomly assigned 8442 patients with class II, III, or IV heart failure and an ejection fraction of 40% or less to receive either LCZ696 (at a dose of 200 mg twice daily) or enalapril (at a dose of 10 mg twice daily), in ...[more]