Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Expression in hypothalamus of wild-derived mice M.m. domesticus


ABSTRACT: We sequenced hypothalamus RNA from 16 individuals from two wild-caught outbred M. m. domesticus populations that consisted of eight unrelated individuals each, from France and Germany

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Mus musculus domesticus

SUBMITTER: Anna Lorenc 

PROVIDER: E-MTAB-3304 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


<h4>Background</h4>We compared the angiotensin receptor-neprilysin inhibitor LCZ696 with enalapril in patients who had heart failure with a reduced ejection fraction. In previous studies, enalapril improved survival in such patients.<h4>Methods</h4>In this double-blind trial, we randomly assigned 8442 patients with class II, III, or IV heart failure and an ejection fraction of 40% or less to receive either LCZ696 (at a dose of 200 mg twice daily) or enalapril (at a dose of 10 mg twice daily), in  ...[more]

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