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MicroRNA microarray in atmpk3 and atmpk6 Arabidopsis mutants

ABSTRACT: MicroRNA microarray profiling was performed in Arabidopsis seedlings - Col-0, atmpk3 and atmpk6 mutants to uncover the roles of MPK3 and MPK6 in microRNA biogenesis pathway.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Alok Sinha

PROVIDER: E-MTAB-3404 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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MicroRNA biogenesis factor DRB1 is a phosphorylation target of mitogen activated protein kinase MPK3 in both rice and Arabidopsis.

Raghuram Badmi B Sheikh Arsheed H AH Rustagi Yashika Y Sinha Alok K AK

The FEBS journal 20141216 3

MicroRNA (miRNA) biogenesis requires AtDRB1 (double-stranded RNA binding protein)/HYL1 (Hyponastic Leaves1) protein for processing and maturation of miRNA precursors. The AtDRB1/HYL1 protein associates with AtDCL1 (Dicer-Like1) and accurately processes primary-miRNAs (pri-mRNAs) first to precursor-miRNAs (pre-miRNAs) and finally to mature miRNAs. The dephosphorylation of AtDRB1/HYL1 protein is very important for the precise processing of miRNA precursors. The monocot model crop plant Oryza sativ ...[more]

PMID: 25417716

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