Unknown,Transcriptomics,Genomics,Proteomics

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Domestication Effects on Stress Induced Steroid Secretion and Adrenal Gene Expression in Chickens


ABSTRACT: Background Understanding the genetic basis of phenotypic diversity is a challenge in contemporary biology. Domestication provides a model for unravelling aspects of this, for example with respect to stress sensitivity. Ancestral Red Junglefowl (RJF) show more fearful behaviour and a more pronounced HPA-axis reactivity than its domesticated descendant White Leghorn (WL). By comparing adrenal global gene transcription profiles between WL and RJF as well as their plasma levels of adrenal hormones in response to an acute stress event, we aimed at investigating the molecular basis for the altered physiological stress responsiveness in domesticated chicken.

INSTRUMENT(S): NimbleGen MS2000, Nimble gene 12 x 135 k custom gene expression arrays

ORGANISM(S): Gallus gallus

SUBMITTER: Amir Fallahshahroudi 

PROVIDER: E-MTAB-3622 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Domestication Effects on Stress Induced Steroid Secretion and Adrenal Gene Expression in Chickens.

Fallahsharoudi Amir A   de Kock Neil N   Johnsson Martin M   Ubhayasekera S J Kumari A SJ   Bergquist Jonas J   Wright Dominic D   Jensen Per P  

Scientific reports 20151016


Understanding the genetic basis of phenotypic diversity is a challenge in contemporary biology. Domestication provides a model for unravelling aspects of the genetic basis of stress sensitivity. The ancestral Red Junglefowl (RJF) exhibits greater fear-related behaviour and a more pronounced HPA-axis reactivity than its domesticated counterpart, the White Leghorn (WL). By comparing hormones (plasmatic) and adrenal global gene transcription profiles between WL and RJF in response to an acute stres  ...[more]

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