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Exogenous BRCT-GST of PARP1 bind to wild-type p53. p53 was overexpressed after UV treatment in U2OS.

ABSTRACT: Exogenous BRCT-GST in U2OS bind to wild-type p53 in a phosphorylation-dependent manner, after UV treatment. BRCT-GST fusion protected cells from apoptotic cell death and impact of miRNAs responsive to p53 activation.

ORGANISM(S): Homo sapiens

SUBMITTER: Marco Galasso

PROVIDER: E-MTAB-3628 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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