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A microRNA microarray analysis of glioblastoma cells under hypoxia compared with normoxia.

ABSTRACT: We performed this microRNA analysis on GBM cells and found that numerous miRNAs were differentially expressed under hypoxia condition. And we noticed that the tumor cells are able to survive in hypoxia and low nutrient microenvironment, resist external pressure and then exhibit invasion and metastasis, and also, reduce the sensitivity to chemotherapy, radiotherapy and immunotherapy. We wanted to screen numerous significantly expressed microRNAs which could mediate the biological process under hypoxia.

ORGANISM(S): Homo sapiens

SUBMITTER: Xing Guo

PROVIDER: E-MTAB-3886 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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