[KIL-d] experiments
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ABSTRACT: In yeast, the extrachromosomal genetic element [KIL-d] alters killer activity of M double stranded RNA killer virus and confers cell resistance against the killer virus. However, its underlying mechanism and the molecular nature of [KIL-d] is unknown. We found [KIL-d] selectively increases the rate of de novo mutation in the killer toxin gene of the viral genome. To verify this hypotesis, we performed deep sequence analysis to calculate mutation rate.
INSTRUMENT(S): Illumina HiSeq 2000
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Genjiro Suzuki
PROVIDER: E-MTAB-3932 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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