Ontology highlight
ABSTRACT:
INSTRUMENT(S): x86_64-apple-darwin13.4.0 (64-bit)
ORGANISM(S): Homo sapiens
SUBMITTER: Kristian Almstrup
PROVIDER: E-MTAB-4187 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Almstrup Kristian K Lindhardt Johansen Marie M Busch Alexander S AS Hagen Casper P CP Nielsen John E JE Petersen Jørgen Holm JH Juul Anders A
Scientific reports 20160628
Puberty marks numerous physiological processes which are initiated by central activation of the hypothalamic-pituitary-gonadal axis, followed by development of secondary sexual characteristics. To a large extent, pubertal timing is heritable, but current knowledge of genetic polymorphisms only explains few months in the large inter-individual variation in the timing of puberty. We have analysed longitudinal genome-wide changes in DNA methylation in peripheral blood samples (n = 102) obtained fro ...[more]