Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Andrew Streets
PROVIDER: E-MTAB-4189 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Streets Andrew J AJ Magayr Tajdida A TA Huang Linghong L Vergoz Laura L Rossetti Sandro S Simms Roslyn J RJ Harris Peter C PC Peters Dorien J M DJ Ong Albert C M AC
American journal of physiology. Renal physiology 20170111 4
Autosomal dominant polycystic kidney disease (ADPKD) is the fourth most common cause of end-stage renal disease. The disease course can be highly variable and treatment options are limited. To identify new therapeutic targets and prognostic biomarkers of disease, we conducted parallel discovery microarray profiling in normal and diseased human <i>PKD1</i> cystic kidney cells. A total of 1,515 genes and 5 miRNA were differentially expressed by more than twofold in <i>PKD1</i> cells. Functional en ...[more]