Contribution from Different Genomic Annotation Sets to Quantitative Trait Variation Revealed by Maize GWAS

ABSTRACT: The genomic distribution of trait-associated SNPs (TASs) discovered in genome-wide association studies (GWAS) can provide insight into the genetic architecture of complex traits and the design of future studies. Here we report on a maize GWAS that identified TASs underlying five quantitative traits measured across a large panel of samples and examine the characteristics of these TASs. A set of SNPs obtained via RNA sequencing (RNA-seq), most of which are located within annotated genes (~87%) were complemented with additional SNPs from the maize HapMap Project that contains approximately equal proportions of intragenic and intergenic SNPs. TASs were identified via a genome scan while controlling for polygenic background effects. The diverse functions of TAS-containing candidate genes indica

INSTRUMENT(S): Illumina Genome Analyzer IIx

ORGANISM(S): Zea mays

SUBMITTER: Patrick Schnable 

PROVIDER: E-MTAB-4233 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress