Dynamic transcriptome analysis reveals mRNA synthesis and decay in yeast
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ABSTRACT: To obtain rates of mRNA synthesis and decay in yeast, we established dynamic transcriptome analysis (DTA). DTA combines non-perturbing metabolic RNA labeling with dynamic kinetic modeling. DTA was used to monitor the cellular response to osmotic stress in comparison to the wild type. Genomic occupancy profiling of RNA polymerase (Pol) II was used to predict changes in mRNA synthesis rates.
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Björn Schwalb
PROVIDER: E-MTAB-439 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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