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Mechanism for full-length RNA processing over intragenic heterochromatin

ABSTRACT: Mechanism for full-length RNA processing over intragenic heterochromatin

INSTRUMENT(S): Illumina Genome Analyzer IIx

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Hidetoshi Saze

PROVIDER: E-MTAB-4475 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Mechanism for full-length RNA processing of Arabidopsis genes containing intragenic heterochromatin.

Saze Hidetoshi H Kitayama Junko J Takashima Kazuya K Miura Saori S Harukawa Yoshiko Y Ito Tasuku T Kakutani Tetsuji T

Nature communications 20130101

Genomes of higher eukaryotes contain many transposable elements, which often localize within the transcribed regions of active genes. Although intragenic transposable elements can be silenced to form heterochromatin, the impact of intragenic heterochromatin on transcription and RNA processing remains largely unexplored. Here we show using a flowering plant, Arabidopsis, that full-length transcript formation over intragenic heterochromatin depends on a protein named IBM2 (Increase in Bonsai Methy ...[more]

PMID: 23934508

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