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Gene expression profiles of intermediate progenitors of GABAergic neuron

ABSTRACT: Intermediate progenitors of GABAergic neurons obtained from the mouse embryo neocortex at E18. Additional info: http://srv02.medic.kumamoto-u.ac.jp/dept/morneuro/en_r_micro.html

ORGANISM(S): Mus musculus

SUBMITTER: Nobuaki Tamamaki

PROVIDER: E-MTAB-452 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Method for single-cell microarray analysis and application to gene-expression profiling of GABAergic neuron progenitors.

Esumi Shigeyuki S Wu Sheng-Xi SX Yanagawa Yuchio Y Obata Kunihiko K Sugimoto Yukihiko Y Tamamaki Nobuaki N

Neuroscience research 20080106 4

The mammalian central nervous system is populated with various types of neurons and glia. To investigate the functions and development of individual cells requires gene-expression analysis at the single-cell level. Here, we developed a microarray-based method for the gene-expression profiling of single cells and tested it for GABAergic neuron progenitors. Single GABAergic neuron progenitors were collected from the neocortex of GAD67-GFP knock-in mice by dissociation followed by the aspiration of ...[more]

PMID: 18280602

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