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Gene expression profiles of GABAergic neuron progenitors (GAD67-GFP-positive cells)

ABSTRACT: Gene expression profiles of GABAergic neuron progenitors (GAD67-GFP-positive cells)

ORGANISM(S): Mus musculus

SUBMITTER: Keisuke Watanabe

PROVIDER: E-MTAB-904 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex.

Watanabe Keisuke K Takebayashi Hirohide H Bepari Asim K AK Esumi Shigeyuki S Yanagawa Yuchio Y Tamamaki Nobuaki N

Development (Cambridge, England) 20111101 22

During corticogenesis, the regulation of neuronal migration is crucial for the functional organization of the neocortex. Glutamatergic neurons are major excitatory components of the mammalian neocortex. In order to elucidate the specific molecular mechanisms underlying their development, we used single-cell microarray analysis to screen for mouse genes that are highly expressed in developing glutamatergic neurons. We identified dpy-19-like 1 (Dpy19l1), a homolog of C. elegans dpy-19, which encod ...[more]

PMID: 22028030

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