Unknown,Transcriptomics,Genomics,Proteomics

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Microarray dataset of Jurkat cells following miR-93 over-expression


ABSTRACT: miR-93 is often dysregulated in several tumor cell lines, including lymphoblastic leukemias. This dataset can represent a further insight into gene expression changes and GO Terms associated with miR-93 over-expression. miR-93 was over-expressed in Jurkat cells by transduction with a lentiviral transgenic construct encoding for miR-93 under a PGK promoter. A cognate vector encoding for a control hairpin was used to generate control cell line. mRNA Microarray gene expression profiling of Jurkat cells tranduced with either a miR-93 sponge or control construct. 3 biological replicas have been performed.

ORGANISM(S): Homo sapiens

SUBMITTER: Silvia Gioiosa 

PROVIDER: E-MTAB-4588 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Microarray dataset of Jurkat cells following miR-93 over-expression.

Gioiosa Silvia S   Verduci Lorena L   Azzalin Gianluca G   Carissimi Claudia C   Fulci Valerio V   Macino Giuseppe G  

Data in brief 20160620


The dataset presented here represents a microarray experiment of Jurkat cell line over-expressing miR-93 after lentiviral transgenic construct transduction. Three biological replicates have been performed. We further provide normalized and processed data, log2 Fold Change based ranked list and GOterms resulting table. The raw microarray data are available in the ArrayExpress database (www.ebi.ac.uk/arrayexpress) under accession number ArrayExpress: E-MTAB-4588. ...[more]

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