Effects of digested onion extracts on intestinal gene expression using rat intestine slices
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Peter Hendriksen
PROVIDER: E-MTAB-5120 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Effects of Digested Onion Extracts on Intestinal Gene Expression: An Interspecies Comparison Using Different Intestine Models.
de Wit Nicole J W NJ Hulst Marcel M Govers Coen C van der Meulen Jan J van Hoef Angeline A Stoopen Geert G Hamers Astrid A Hoekman Arjan A de Vos Ric R Bovee Toine F H TF Smits Mari M Mes Jurriaan J JJ Hendriksen Peter J M PJ
PloS one 20160915 9
Human intestinal tissue samples are barely accessible to study potential health benefits of nutritional compounds. Numbers of animals used in animal trials, however, need to be minimalized. Therefore, we explored the applicability of in vitro (human Caco-2 cells) and ex vivo intestine models (rat precision cut intestine slices and the pig in-situ small intestinal segment perfusion (SISP) technique) to study the effect of food compounds. In vitro digested yellow (YOd) and white onion extracts (WO ...[more]
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