Transcription profiling of mouse hippocampal slices after NMDA or forskolin-rolipram-0 Mg2+ or bicuculline treatment
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Luis Valor
PROVIDER: E-MEXP-1184 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Kinase networks integrate profiles of N-methyl-D-aspartate receptor-mediated gene expression in hippocampus.
Coba Marcelo P MP Valor Luis M LM Kopanitsa Maksym V MV Afinowi Nurudeen O NO Grant Seth G N SG
The Journal of biological chemistry 20080923 49
The postsynaptic N-methyl-d-aspartate (NMDA) receptor activates multiple kinases and changes the phosphorylation of many postsynaptic proteins organized in signaling networks. Because the NMDA receptor is known to regulate gene expression, it is important to examine whether networks of kinases control signaling to gene expression. We examined the requirement of multiple kinases and NMDA receptor-interacting proteins for gene expression in mouse hippocampal slices. Protocols that induce long-term ...[more]
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