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Unknown,Transcriptomics,Genomics,Proteomics

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The International Cancer Genome project: Pan-Cancer Analysis of Whole Genomes (PCAWG)- Alternative view by individual

ABSTRACT: The Pan-Cancer Analysis of Whole Genomes (PCAWG) study is an international collaboration to identify common patterns of mutation in more than 2,800 cancer whole genomes from the International Cancer Genome Consortium. Building upon previous work which examined cancer coding regions, this project is exploring the nature and consequences of somatic and germline variations in both coding and non-coding regions, with specific emphasis on cis-regulatory sites, non-coding RNAs, and large-scale structural alterations. Read more on the project website.
This is a subset featuring RNA-seq transcription profiling data of 27 cancer subtypes in 19 tissues. Some donors have matched normal tissue.
This is the alternative view of the experiment for Expression Atlas to show gene expression per donor.

INSTRUMENT(S): Illumina HiSeq 2500, Illumina Genome Analyzer II, Illumina Genome Analyzer IIx, Illumina HiSeq, Illumina HiSeq 2000

ORGANISM(S): Homo sapiens

SUBMITTER: ArrayExpress curator

PROVIDER: E-MTAB-5423 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The International Cancer Genome project: Pan-Cancer Analysis of Whole Genomes (PCAWG)

Project description:The Pan-Cancer Analysis of Whole Genomes (PCAWG) study is an international collaboration to identify common patterns of mutation in more than 2,800 cancer whole genomes from the International Cancer Genome Consortium. Building upon previous work which examined cancer coding regions, this project is exploring the nature and consequences of somatic and germline variations in both coding and non-coding regions, with specific emphasis on cis-regulatory sites, non-coding RNAs, and large-scale structural alterations. Read more on the <a href=\"https://dcc.icgc.org/pcawg\" target=\"_blank\">project website</a>. This is a subset featuring RNA-seq transcription profiling data of 27 cancer subtypes in 19 tissues. Some donors have matched normal tissue. As general reference, a subset of normal tissue samples from the GTEx project were included in this experiment.

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E-MTAB-5200

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