Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Microarray analysis of human A549 lung cancer cells treated with brefeldin A, golgicide A, monensin or vehicle control for 8 h or 20 h

ABSTRACT: A549 cells were treated for 8 or 20 h using 20 ng/mL brefeldin A (BFA), 5 µM golgicide A (GCA), 10 µM monensin (MON) or the appropriate vehicle control (BFA/EtOH, MON/EtOH, GCA/DMSO).

ORGANISM(S): Homo sapiens

SUBMITTER: Jan Baumann 

PROVIDER: E-MTAB-5627 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Golgi stress-induced transcriptional changes mediated by MAPK signaling and three ETS transcription factors regulate MCL1 splicing.

Baumann Jan J   Ignashkova Tatiana I TI   Chirasani Sridhar R SR   Ramírez-Peinado Silvia S   Alborzinia Hamed H   Gendarme Mathieu M   Kuhnigk Kyra K   Kramer Valentin V   Lindemann Ralph K RK   Reiling Jan H JH  

Molecular biology of the cell 20171108 1

The secretory pathway is a major determinant of cellular homoeostasis. While research into secretory stress signaling has so far mostly focused on the endoplasmic reticulum (ER), emerging data suggest that the Golgi itself serves as an important signaling hub capable of initiating stress responses. To systematically identify novel Golgi stress mediators, we performed a transcriptomic analysis of cells exposed to three different pharmacological compounds known to elicit Golgi fragmentation: brefe  ...[more]

Similar Datasets

Transcriptomics Estrogen-like activity and dual roles in cell signaling of brefeldin A
2014-01-01 | GSE33851 | GEO
Transcriptomics Gene expression profiling of HepG2 cells after treatment with Brefeldin A
2017-09-01 | GSE94861 | GEO
Transcriptomics RNA-seq of MV4;11 cells treated with Methyl Bestatin or Brefeldin A
2022-11-15 | GSE200454 | GEO
Genomics Whole genome sequencing of brefeldin A adaptors in Cryptococcus neoformans
2022-10-15 | E-MTAB-12220 | biostudies-arrayexpress
Transcriptomics Whole genome sequencing of Candida albicansSC5314 treated with brefeldin A
2021-04-23 | E-MTAB-10351 | biostudies-arrayexpress
Genomics Whole genome sequencing of adaptors selected by sub-inhibitory amount of brefeldin A in Candida albicans
2023-10-06 | E-MTAB-12490 | biostudies-arrayexpress
Transcriptomics Transecriptome analysis of Cryptococcus neoformans exposed to ER stress inducer brefeldin A
2022-10-24 | E-MTAB-12285 | biostudies-arrayexpress
Transcriptomics Estrogen-like activity and dual roles in cell signaling of brefeldin A
2014-01-01 | E-GEOD-33851 | biostudies-arrayexpress
Genomics Whole genome sequencing of Chr3x3 derived brefeldin A adpators in Candida albicans
2023-09-07 | E-MTAB-12510 | biostudies-arrayexpress
Genomics Whole genome sequencing of Cryptococcus neoformans adaptors derived from exposure to supra-MIC amount of brefeldin A
2022-10-31 | E-MTAB-12318 | biostudies-arrayexpress