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Time series of gene expression profiles describing the temporal response to prolonged heat stress in C. elegans.

ABSTRACT: This experiment broadens our understanding of the temporal dynamics underlying the transcriptional response to heat stress. Using C. elegans hermaphrodite N2 populations, we have created a high-resolution time series of gene expression profiles taken at different time points during prolonged heat stress (35 C) conditions. Samples ware taken after 0h, 0.5h, 1h, 2h, 3h, 4h, 6h, 8h, and 12h of heat exposure with 3-5 biological replicas per time point.

INSTRUMENT(S): Promega MaxwellÂ® 16 AS2000

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Katharina Jovic

PROVIDER: E-MTAB-5753 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Recovery time-series after increasing heat-stress exposures in Caenorhabditis elegans measured by microarray

Project description:Increased exposure to heat-stress leads to an increasingly altered transcriptome in Caenorhabditis elegans. It is however unclear how the recovery from heat-stress progresses after increased heat-stress exposures. Hence, we exposed populations of the N2 strain to a 2, 3, 4, or 6 hour heat-shock of 35 degrees Celsius and took samples from 1 - 4 hours after termination of stress. This experiment was conduced in three biological replicates.

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Time series of gene expression profiles from C. elegans exposed to heat-stress and during subsequent recovery

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2019-05-29 | E-MTAB-7424 | biostudies-arrayexpress

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2023-10-24 | PXD040281 | Pride

Operation of a TCA cycle subnetwork in the mammalian nucleus

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2019-07-12 | E-MTAB-8129 | biostudies-arrayexpress

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