Unknown,Transcriptomics,Genomics,Proteomics

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Methylation arrays delineate the extent of 5mC and 5hmC in human brain and glioma samples.


ABSTRACT: The link between global reductions in 5-hydroxymethylcytosine levels and cancer is well-known. In this study, we have characterized the extent and the location of 5hmC loss in brain tumors. We performed genome-wide methylation oxBS and BS analyses with the Illumina Infinium HumanMethylation450 BeadChip platform in 5 brain and 9 glioma samples and we measured the extent of 5mC and 5hmC in these normal versus tumoral conditions.

ORGANISM(S): Homo sapiens

SUBMITTER: Agustin F. Fernandez 

PROVIDER: E-MTAB-6003 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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