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Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens

ABSTRACT: Single-cell transcriptome profiling using a 3' droplet-based platform (Chromium,10x Genomics) of CD11b+ cells isolated from the spleen of control and tumor-bearing mice, treated or not with IFN gene therapy.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Mus musculus

SUBMITTER: Luigi Naldini

PROVIDER: E-MTAB-6487 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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RNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment

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