Dataset Information
ChIP-seq of HNF4A and GATA6 in oesophageal adenocaricnoma OE19 cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Homo sapiens
SUBMITTER: Andrew Sharrocks
PROVIDER: E-MTAB-6858 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Identification of a primitive intestinal transcription factor network shared between esophageal adenocarcinoma and its precancerous precursor state.
Genome research 20190408 5
Esophageal adenocarcinoma (EAC) is one of the most frequent causes of cancer death, and yet compared to other common cancers, we know relatively little about the molecular composition of this tumor type. To further our understanding of this cancer, we have used open chromatin profiling to decipher the transcriptional regulatory networks that are operational in EAC. We have uncovered a transcription factor network that is usually found in primitive intestinal cells during embryonic development, c ...[more]
