Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2500
ORGANISM(S): Homo sapiens
SUBMITTER: Olivier LANTZ
PROVIDER: E-MTAB-7143 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Salou Marion M Legoux François F Gilet Jules J Darbois Aurélie A du Halgouet Anastasia A Alonso Ruby R Richer Wilfrid W Goubet Anne-Gaëlle AG Daviaud Céline C Menger Laurie L Procopio Emanuele E Premel Virginie V Lantz Olivier O
The Journal of experimental medicine 20181205 1
Mucosal-associated invariant T (MAIT) cells are abundant T cells with unique specificity for microbial metabolites. MAIT conservation along evolution indicates important functions, but their low frequency in mice has hampered their detailed characterization. Here, we performed the first transcriptomic analysis of murine MAIT cells. MAIT1 (RORγt<sup>neg</sup>) and MAIT17 (RORγt<sup>+</sup>) subsets were markedly distinct from mainstream T cells, but quasi-identical to NKT1 and NKT17 subsets. The ...[more]